Pharmacogenomics Primer


Program Details

  • Intended Audience: Pharmacists interested in precision medicine.
  • UAN: 0012-0000-17-258-H04-P
  • CE Hours: 2.75 General
  • Price: $25.00
  • Dates Available: 10/03/2017-10/03/2020
  • Activity Type: Knowledge

Summary

This course will summarize the principles of drug metabolism pharmacogenetics and genetic medicine.

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Objectives

  • Pharmacogenetics of Drug Metabolism: Parts 1-5
    • Summarize scientific principles of pharmacogenomics, including discussion of:
      • Human genetics.
      • Relationship between genotypes and phenotypes in the context of pharmacogenomics.
      • Types of polymorphisms, including single nucleotide polymorphisms.
      • Linkage disequilibrium.
      • Haplotypes and diplotypes.
      • Star-allele nomenclature.
    • Discuss the different types of studies in the pharmacogenomics literature and their corresponding levels of evidence.
    • Explain the contribution of pharmacokinetics and genetics to interindividual variability in response.
    • Discuss relevant genetic polymorphisms of important drug metabolizing enzymes and their potential clinical implications.
    • Explain the function and tissue distribution of drug transporters.
    • Discuss variations in drug transporters and their clinical significance
    • Compare pharmacogenetics and therapeutic drug monitoring (TDM)
    • List example drugs for which pharmacogenetics-guided TDM may be the most useful

    Principles of Genetic Medicine: Parts I-2

    • Review DNA.
    • Explain the Human Genome Project.
    • Discuss the Central Dogma of Molecular Biology.
    • Discuss the Types of polymorphisms.
    • Define allele, genotype, and phenotype
    • Define linkage disequilibrium, haplotype, and diplotype
    • Introduce PharmGKB

Acknowledgements and Disclosures

The following speakers, reviewers, and planning committee members have disclosed that he/she has no relevant financial disclosures. No one else in a position to control content has any financial relationships to disclose.

Caitrin W. McDonough, Ph.D.
Research Assistant Professor
Department of Pharmacotherapy and Translational Research
College of Pharmacy, University of Florida

Reginald F. Frye, Pharm.D., Ph.D., FCCP
Professor and Chair
Department of Pharmacotherapy and Translational Research
College of Pharmacy, University of Florida

Kristin Weitzel, Pharm.D., CDE, FAPhA
Associate Director, UF Health Personalized Medicine Program
Director, Continuing Pharmacy Education
Editor-in-Chief, Pharmacy Today
Clinical Professor, Pharmacotherapy and Translational Research
University of Florida

Priti Patel, PharmD, BCPS
Clinical Associate Professor
College of Pharmacy, University of Florida

 

Schedule of Activities

Review all course materials and pass post-test with 70% or more.

Requirements for Successful Course Completion

View recorded lectures, receive a 70% or higher on final exam and complete course evaluation.

Credit Reporting

  • The University of Florida College of Pharmacy will report CPE credit to CPE Monitor and CE Broker when applicable. If you would like a paper statement of credit, you may print it from your NABP e-profile.
  • All pharmacists and pharmacy technicians maintain their own license and/or certification and it is their responsibility to follow up with the Office of Continuing Education at the University of Florida if any CE credit discrepancies are found.
  • It is at the University’s discretion to award or deny credit to a late claiming participant (i.e. after 60 days of the participant engaging in a CPE activity) as it is the University’s CE activity and the provider needs to ensure the requirements necessary for credit are successfully completed.
  • The University may request access to CPE Monitor® if the activity in question occurred within the previous 6 months and with an appropriate reason for access, i.e. power outage, etc.

Program Financial Support

This course received no outside funding support.

Computer Requirements

Computer and Internet access are required to complete this course. Course content is provided via Canvas.

The minimum hardware, software, and Internet requirements for Canvas can be found here.

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Copyright

This course in its entirety is copyrighted by the University of Florida Continuing Pharmacy Education and may not be duplicated or reproduced for any other purpose without specific written permission.

For questions or more information, please contact our office.


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